Esophageal spasms are painful contractions in the muscular tube connecting the mouth and stomach, called the esophagus. Esophageal spasms can feel like sudden, bad chest pain that lasts from a few minutes to hours. Some people may mistake it for heart pain, also called angina.

Esophageal spasms usually happen only now and then, and they might not need treatment. But sometimes the spasms happen a lot and can prevent food and liquids from traveling through the esophagus. If esophageal spasms affect the ability to eat or drink, treatments are available.

Symptoms of esophageal spasms include:

  • Squeezing pain in the chest. The pain is often intense and might be mistaken for heart pain or heartburn.
  • Difficulty swallowing solids and liquids, sometimes related to swallowing specific substances. Red wine or extremely hot or cold liquids are more common culprits.
  • The feeling that an object is stuck in the throat.
  • The return of food and liquids back up the esophagus, also called regurgitation.

When to see a doctor

The squeezing chest pain that happens with esophageal spasms also can be caused by a heart attack. If you have squeezing chest pain, seek medical care right away.

It’s not clear what causes esophageal spasms. However, they appear to be related to abnormal functioning of nerves that control the muscles used when swallowing.

A healthy esophagus moves food into the stomach through a series of coordinated muscle contractions. Esophageal spasms make it difficult for the muscles in the walls of the lower esophagus to coordinate. This makes it harder for the muscles to move food to the stomach.

There are two types of esophageal spasms — distal esophageal spasm and hypercontractile esophagus, also known as nutcracker esophagus.

Risk factors for esophageal spasms include:

  • Sex. Women are more likely to have esophageal spasms than men.
  • Age. Esophageal spasms tend to happen around age 60.

To diagnose esophageal spasms, a healthcare professional may recommend:

  • Upper endoscopy. An upper endoscopy uses a tiny camera on the end of a flexible tube to visually examine the upper digestive system. Endoscopy also can be used to collect a sample of tissue to be tested for other esophageal diseases. This tissue sample is known as a biopsy.
  • X-rays of the upper digestive system, also called an esophagram. X-rays are taken after drinking a chalky liquid that coats and fills the inside lining of the digestive tract. The coating allows a specialist to see a silhouette of the esophagus, stomach and upper intestine. Some people may experience loose stools for 1 to 2 days after this test.
  • Esophageal manometry. This test measures the rhythmic muscle contractions in the esophagus when swallowing; the coordination and force exerted by the esophagus muscles; and how well the lower esophageal sphincter relaxes or opens during a swallow.

Treatment depends on how often the esophageal spasms happen and how bad they are.

If the spasms only happen now and then, a healthcare professional might first recommend avoiding extremely hot or cold foods to see if that relieves symptoms.

If your spasms make it difficult to eat or drink, your provider might recommend:

  • Managing any underlying conditions. Esophageal spasms are sometimes associated with conditions such as heartburn or gastroesophageal reflux disease (GERD). A healthcare professional might recommend a proton pump inhibitor to treat GERD. Sometimes an antidepressant, such as imipramine, may be prescribed. This medicine may help reduce the feeling of pain in the esophagus.
  • Medicines to relax your swallowing muscles. Peppermint oil, onabotulinumtoxinA (Botox) injections into the esophagus or calcium channel blockers, such as diltiazem (Cardizem, Tiazac, others), can make spasms less severe.
  • Surgery (myotomy). If medicine doesn’t work, a healthcare professional might recommend a procedure that involves cutting the muscle at the lower end of the esophagus. This procedure, called a myotomy, can help weaken esophageal contractions. Long-term studies of this approach aren’t available, so myotomy generally isn’t recommended for esophageal spasms. However, it might be considered if other treatments don’t work.
  • Peroral endoscopic myotomy (POEM). The POEM procedure is minimally invasive. This newer technique involves placing an endoscope through the mouth and down the throat. This allows a surgeon to make a cut in the inside lining of the esophagus. Then, as in standard myotomy, the surgeon cuts the muscle at the lower end of the esophagus. Like standard myotomy, POEM is usually considered only if other treatments don’t work.
  1. Townsend CM Jr., et al. Esophagus. In: Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 21st ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed Sept. 9, 2024.
  2. Distal esophageal spasm (corkscrew esophagus; diffuse esophageal spasm). Merck Manual Professional Version. https://www.merckmanuals.com/professional/gastrointestinal-disorders/esophageal-and-swallowing-disorders/distal-esophageal-spasm. Accessed Sept. 9, 2024.
  3. Talley NJ. Distal esophageal spasm and hypercontractile esophagus. https://www.uptodate.com/contents/search. Accessed Sept. 9, 2024.
  4. Distal esophageal spasm: An updated review. Cureus. 2023; doi:10.7759/cureus.41504.
  5. Medical review (expert opinion). Mayo Clinic. Sept. 23, 2024.
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