In Zenker’s diverticulum, a bulge or pouch forms at the top of the tube that connects the throat to the stomach, called the esophagus. The condition is not common. Connected bands of muscle that work to pass food from the mouth to the stomach make up the esophagus.

Over time, the bulge of Zenker’s diverticulum can get bigger. Food, pills and even thick mucus can get stuck in the pouch instead of going through the esophagus. This can lead to problems with eating and other complications.

The cause of Zenker’s diverticulum is not known. It happens most often to men older than 60. Treatment for symptoms of Zenker’s diverticulum often is surgery.

A small Zenker’s diverticulum may not have any symptoms. But the bulge may get bigger over time. It can trap food, mucus and pills. Symptoms might include:

  • Trouble swallowing, called dysphagia.
  • Burping.
  • A gurgling noise at the back of the throat.
  • Coughing.
  • Hoarseness.
  • Bad breath.
  • Choking.

If the pouch gets big enough, what’s in it may spill into the throat. Then Zenker’s diverticulum symptoms might include:

  • Feeling of food stuck in the throat.
  • Coughing up or spitting up food 1 to 2 hours after eating. This is called regurgitation.
  • Breathing food into the lungs, called aspirating.
 

The cause of Zenker’s diverticulum isn’t known. It’s not known why the walls of the esophagus change to form a bulge or pouch in the condition.

The cause of Zenker’s diverticulum might involve the muscles of the esophagus not working together. Most often, a muscle at the top of the esophagus relaxes to let the food down. If that doesn’t happen, food can get trapped in the esophagus.

If the muscle in the area where the food gets trapped is weak, the food can cause the esophagus to bulge and form a pouch.

Risk factors for Zenker’s diverticulum include:

  • Being older than 60.
  • Being male.
  • Having gastroesophageal reflux disease (GERD) or a condition in which part of the stomach bulges into the chest, called a hiatal hernia.
  • Having spinal surgery.

Complications can happen if Zenker’s diverticulum isn’t treated. The bulge of Zenker’s diverticulum can get larger if it’s not treated. Complications of Zenker’s diverticulum can include:

  • Lung infection. Breathing in food, called aspirating, can lead to a lung infection. This is called aspiration pneumonia.
  • Weight loss and not getting enough nutrients, called malnutrition. Trouble swallowing can lead to weight loss and malnutrition.

To diagnose Zenker’s diverticulum, a healthcare professional, often an ear, nose and throat (ENT) specialist, does a physical exam and asks about your symptoms.

Tests

The test most often done to diagnose Zenker’s diverticulum is a barium swallow. In this test, a specialist takes a series of X-rays of the digestive tract after you swallow a liquid that coats the walls of the digestive tract. The liquid, called barium sulfate, makes the digestive tract easier to see on X-ray.

To treat Zenker’s diverticulum, surgery or other procedures may be needed. Eating softer foods in smaller bites might help with swallowing if you have mild symptoms of Zenker’s diverticulum. Your healthcare professional might suggest a dietician to help you learn what to eat.

Types of surgeries or other procedures

Repairing the esophagus with a procedure or surgery is the most common treatment for Zenker’s diverticulum that’s causing symptoms. Often, ear, nose and throat conditions (ENT) specialists do the procedure or surgery. They often do the procedure through a tube called an endoscope that goes into the mouth to the esophagus. This is less invasive than open surgery.

Endoscope procedures to repair Zenker’s diverticulum, sometimes called endoscopic repairs, most often have shorter surgery times and may have a shorter hospital stay compared to open surgery. They also often have similar results and improve Zenker’s diverticulum symptoms for people as much as open surgery. But people who have endoscope procedures might have a higher risk of a Zenker’s diverticulum coming back.

There are two main types of endoscope procedures used to repair Zenker’s diverticulum. They each take about 1 to 2 hours to do.

  • Rigid endoscope procedure. Before the procedure, you’re given medicine called general anesthesia to put you into a sleeplike state. The ENT specialist uses a rigid endoscope to get to the esophagus. A rigid endoscope doesn’t bend or twist. The ENT specialist often uses a laser or may use a stapler to widen the opening to the bulge.

    Sometimes, the ENT specialist can remove the pouch with the laser device. This is called an endoscopic diverticulectomy. Electrocautery is another choice, but it’s rarely used with the rigid endoscope procedure.

  • Flexible endoscope procedure. Before this procedure, you may get medicine that causes a near sleeplike state, called deep sedation, or general anesthesia. The endoscope is flexible. A surgeon uses an electric current, called electrocautery, to cut the bulge. Clips may be used for any bleeding.

Repairing Zenker’s diverticulum sometimes may need to be done in an open surgery, sometimes called an open repair. Before the procedure, you’re given general anesthesia. The ENT specialist makes a cut, called an incision, in the neck to remove the bulge.

This surgery most often takes 2 to 3 hours. People who have this type of surgery often stay in the hospital for one or more days. This surgery eases symptoms for most people.

Possible complications

Possible complications of surgery to repair Zenker’s diverticulum may include:

  • Infection.
  • Blood clots.
  • Reactions to anesthesia.
  • A hole in the esophagus.
  • Dental injury such as a chipped tooth when surgery is done using an endoscope.

Results

Both endoscopic and open surgery ease Zenker’s diverticulum symptoms for most people. Endoscope procedures most often have shorter surgery times. Hospital stays often are just one night for endoscopic and open surgeries.

Open surgery leaves a small scar in the neck. Open surgery also can have a bit higher risk of a hole in the esophagus compared to endoscopic techniques. For a large Zenker’s diverticulum, open surgery may be the best choice for full removal of the pouch.

If the first procedure doesn’t ease symptoms or if Zenker’s diverticulum comes back, you may need another procedure. And if Zenker’s diverticulum comes back, it often has no symptoms. Researchers study newer ways of fixing the condition.

  1. Ferri FF. Zenker diverticulum. In: Ferri’s Clinical Advisor 2024. Elsevier; 2024. https://www.clinicalkey.com. Accessed March 22, 2024.
  2. AskMayoExpert. Zenker diverticulum and cricopharyngeal dysfunction (adult). Mayo Clinic; 2023.
  3. Zenker’s diverticulum. ENThealth. https://www.enthealth.org/conditions/zenkers-diverticulum/. Accessed March 22, 2024.
  4. Flint PW, et al., eds. Zenker diverticulum. In: Cummings Otolaryngology: Head & Neck Surgery. 7th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed March 22, 2024.
  5. Van Delft F. Zenker’s diverticulum. https://www.uptodate.com/contents/search. Accessed March 22, 2024.
  6. Fair L, et al. Modern approaches to treating Zenker’s diverticulum. Current Opinion in Gastroenterology. 2023; doi:10.1097/MOG.0000000000000941.
  7. Townsend CM Jr, et al. Esophagus. In: Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 21st ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed March 28, 2024.
  8. Wagh M, et al. How to approach a patient with Zenker’s diverticulum. Gastroenterology. 2021; doi:10.1053/j.gastro.2020.11.018.
  9. Wallerius KP, et al. Comparing open versus rigid endoscopic and flexible endoscopic techniques for the treatment of Zenker’s diverticulum. Otolaryngology – Head and Neck Surgery. 2023; doi:10.1002/ohn.318.
  10. Medical review (expert opinion). Mayo Clinic. Accessed April 18, 2024.
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