You might need to have a cholecystectomy, surgery to remove your gallbladder, if you have a chronic or persistent gallbladder disease. Gallstones are the most common reason. If you have this surgery, you’ll be in good company. It’s one of the most common procedures performed worldwide. In the U.S., most surgeons offer it as a laparoscopic procedure.

A cholecystectomy is a surgical operation to remove your gallbladder — the small, hollow organ that stores bile for your digestive system. Gallbladder removal surgery is a common treatment for gallbladder disease because these conditions often cause more problems than the surgery. You can live a healthy life without a gallbladder.

Gallstones are the most common reason for a cholecystectomy. Some people have no symptoms, but those who do often have repeat issues.

You might need gallbladder removal surgery if gallbladder disease:

  • Interferes with your quality of life.
  • Poses significant risks to your health.
  • Is expected to continue and/or get worse.

That’s often true for conditions like:

  • Chronic cholecystitis.
  • Gallbladder cancer.

Gallbladder removal changes how bile flows in your body. Instead of storing extra bile for digestion, your liver sends it straight to your small intestine.

Most people experience a temporary adjustment period in their digestive systems after gallbladder removal. For the first month or so, you might have more trouble digesting fats and heavier meals. This should gradually improve over time.

Most people can resume a normal, healthy eating plan after their recovery. But a small number of people develop longer-term digestive difficulties, for unclear reasons.

Cholecystectomy is a common procedure with a relatively easy recovery. Surgeons do most laparoscopically, using small incisions to reduce pain and speed healing. Sometimes, people need open surgery, but laparoscopic is the standard.

To get you ready for surgery, your care team will:

  • Run lab tests to make sure you’re healthy enough for the procedure, and if not, they may suggest a temporary alternative, like a cholecystostomy
  • Explain the surgery and get your consent (they’ll let you know if they’re planning an open or laparoscopic operation — though that may change during surgery)
  • Ask you to avoid eating, smoking and certain medications beforehand to help prevent complications

When it’s time, you’ll get an IV for fluids and medicine. You’ll go under general anesthesia. A breathing tube will help keep your airway open during surgery.

Laparoscopic surgery:

Your surgeon will:

  • Make a small incision near your belly button and two to three more in your upper right abdomen.
  • Inflate your abdomen with gas to create space.
  • Insert a laparoscope (camera) to view the area on a monitor.
  • Use thin tools to remove your gallbladder.
  • Release the gas and close the incisions with stitches.

Open surgery:

Your surgeon will:

  • Make a 4- to 6-inch incision under your right ribs.
  • Remove the gallbladder using standard surgical tools.
  • Place a drain, if needed, and close the incision with stitches.

A laparoscopic cholecystectomy normally takes about 60 to 90 minutes. An open cholecystectomy takes about one to two hours. It may take longer if your surgeon also checks or clears your bile ducts during surgery.

Most gallstones develop inside your gallbladder, so removing your gallbladder significantly reduces the chance that you’ll have any more. If gallstones have brought you to the hospital once, they’re likely to do so again. Cholecystectomy is the only treatment that can reliably prevent this. Most people feel it’s easier to have a planned procedure than to expect to have repeat episodes of gallstone emergencies.

There’s always a small risk of complications during surgery.

Specific risks of cholecystectomy include:

  • Pancreatitis (irritation of your pancreas).
  • Bile reflux (traces of bile escape into your stomach).
  • Injury to nearby blood vessels, causing excessive bleeding.
  • Bile duct injury, causing bile leakage.
 

Treatments that suppress your ovaries include:

  • LHRH analogs, including goserelin and leuprolide, which cause temporary menopause.
  • Chemotherapy, which may permanently damage your ovaries.

Chemical castration drugs start working as soon as you start the treatment. They keep working as long as you take them. But over time, prostate cancers may continue to grow, even if your androgen levels are very low (castration-resistant tumors). If you have a castration-resistant tumor, a healthcare provider may recommend different treatments, such as surgically removing your prostate (prostatectomy) or testicles.

After chemical castration, you’ll have a low sex drive (libido) and a reduced response to mental or physical stimulation. For example, you may not get an erection from watching or reading erotic material or touching your genitals and other sensitive parts of your body. You also may not think about sexual intercourse as often.

After surgery, you’ll spend a few hours in a recovery room while you wake up from the anesthesia. You’ll have pain medication as needed. If you had a laparoscopic cholecystectomy, you might be able to go home the same day. If you had an open cholecystectomy, you’ll need to spend a few days recovering in the hospital. Your drain may remain in place for a few days. In some cases, you might go home with it.

The recovery time from a laparoscopic cholecystectomy is about two weeks. Recovery from an open cholecystectomy takes six to eight weeks. If you still have a drain in your wound, your healthcare team will remove it at your next appointment. Most people can return to work after one to two weeks. But if you do a lot of physical activity, you might need to modify your routine until you’re fully recovered.

You may need to adjust your diet after gallbladder removal. Surgery and anesthesia can affect your digestive system, and your body will need time to adapt to the change in how it gets bile. Start with simple, bland foods — similar to what you’d eat if you had the flu. You may have trouble digesting high-fiber or high-fat foods at first. Your provider will guide you as you return to a normal, healthy eating pattern.

Most people have only short-term side effects during their recovery from cholecystectomy surgery. These might include:

  • Diarrhea: This can happen as your digestive system adjusts to its new structure.
  • Constipation: This can occur as a side effect of pain medications.
  • Gas and gas pain: This is a side effect of the gas they use in laparoscopic surgery.
  • Nausea: This can be an effect of your pain medications.

Your healthcare provider can offer advice on how to manage these short-term conditions.

Long-term effects of gallbladder removal

A small percentage of people experience longer-lasting symptoms after a cholecystectomy. Healthcare providers refer to this as post-cholecystectomy syndrome. But these symptoms, and their possible causes, are wide-ranging and don’t really describe one single condition. Post-cholecystectomy syndrome is usually a temporary diagnosis. It stands in until a provider can make a more specific one.

Symptoms can include:

  • Nausea
  • Indigestion
  • Acid reflux
  • Gas and bloating
  • Diarrhea
  • Abdominal pain
  • Jaundice

Most people have one or a few of these symptoms, but not all.

Possible contributing causes include:

  • Preexisting digestive diseases that were previously undiagnosed
  • Gallstones remaining in your bile ducts, or new ones forming there
  • Functional disorders of the biliary tract (biliary dyskinesia)
  • Unexplained pain syndromes (visceral hypersensitivity)
  • Complications from surgery, like bile leakage or pancreatitis

Healthcare providers treat these symptoms and conditions on a case-by-case basis.

Your healthcare provider will schedule a follow-up appointment with you a few weeks after your surgery. But be sure to contact them sooner if you develop symptoms of illness, like:

  • A fever (over 101 degrees Fahrenheit or 38 degrees Celsius).
  • Excessive or increasing pain.
  • Swelling, skin discoloration or discharge from your incision.
  • Persistent nausea and vomiting.
  • Jaundice (a yellow tint to your skin and eyes).
  • Dark-colored pee (urine) or light-colored poop (stool).

When should I call a healthcare provider?

Call a healthcare provider if you have any signs or symptoms that worry you, including existing symptoms that get worse or new symptoms that appear. In most cases, a provider will give you specific things to look out for. But it’s always a good idea to reach out if you have any questions or issues.

  • Asad U, Wang CF, Jones MW. Laparoscopic Cholecystectomy (https://www.ncbi.nlm.nih.gov/books/NBK448145/). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. Updated 7/2/2025. Accessed 7/24/2025.
  • Jones MW, Guay E, Deppen JG. Open Cholecystectomy (https://www.ncbi.nlm.nih.gov/books/NBK448176/). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. Updated 4/23/2023. Accessed 7/24/2025.
  • National Health Service (UK). Gallbladder Removal (https://www.nhs.uk/tests-and-treatments/gallbladder-removal/). Accessed 7/24/2025.
  • National Library of Medicine (U.S.). Gallbladder removal – open – discharge (https://medlineplus.gov/ency/patientinstructions/000118.htm). Last reviewed 9/30/2024. Accessed 7/24/2025.
  • Zackria R, Lopez RA. Postcholecystectomy Syndrome (https://www.ncbi.nlm.nih.gov/books/NBK539902/#:~:text=The%20symptoms%20include%20fatty%20food,months%20to%20years%20after%20surgery.).In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. Updated 8/28/2023. Accessed 7/24/2025.
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