Thoracic Aortic Aneurysm
A thoracic aortic aneurysm is a weakened area in the body’s main artery in the chest. The body’s main artery is called the aorta. When the aortic wall is weak, the artery may get wider. When the artery gets very wide, it’s called an aneurysm. An aneurysm can happen anywhere in the thoracic aorta, including near the heart.
A thoracic aortic aneurysm also is called a thoracic aneurysm. If the aneurysm is between the upper and lower parts of the aorta, it’s called a thoracoabdominal aneurysm.
Thoracic aortic aneurysms are less common than aneurysms in the lower part of the aorta, called abdominal aortic aneurysms.
Treatment of a thoracic aortic aneurysm depends on the cause and size of the aneurysm and how fast it’s growing. Treatment may range from regular health checkups to emergency surgery. A thoracic aortic aneurysm that ruptures or causes a tear called a dissection is a medical emergency that can lead to death.
Thoracic aortic aneurysms often grow slowly. There are usually no symptoms. That makes them hard to find. Many start small and stay small. Others get bigger over time. How quickly a thoracic aortic aneurysm may grow is hard to predict.
As a thoracic aortic aneurysm grows, symptoms may include:
- Back pain.
- Cough.
- Weak, scratchy voice.
- Shortness of breath.
- Tenderness or pain in the chest.
Symptoms that a thoracic aortic aneurysm has ruptured or caused a tear called an aortic dissection include:
- Sharp, sudden pain in the upper back that spreads down the body.
- Pain in the chest, jaw, neck or arms.
- Trouble breathing.
- Low blood pressure.
- Loss of consciousness.
- Shortness of breath.
- Trouble swallowing.
Some aneurysms may never rupture or lead to dissection.
When to see a doctor
Most people with thoracic aortic aneurysms don’t have symptoms until an aortic dissection or rupture occurs. An aortic dissection or aneurysm rupture is a medical emergency. Call 911 or your local emergency number for immediate help.
Causes of thoracic aortic aneurysms may include:
- Atherosclerosis. A buildup of fats, cholesterol, and other substances in and on the artery walls causes the arteries to get stiff. Over time, the walls of the arteries may get weak. High blood pressure and high cholesterol increase the risk of atherosclerosis, especially in older people.
Genetic conditions. Aortic aneurysms in younger people are often caused by changes in genes. A genetic condition called Marfan syndrome can weaken the wall of the aorta.
If you have Marfan syndrome or a related condition, such as Loeys-Dietz syndrome or vascular Ehlers-Danlos syndrome, you have a much higher risk of a thoracic aortic aneurysm. These conditions also make you more likely to have an aortic rupture or aortic dissection.
- Blood vessel inflammation. Conditions that cause irritation and swelling of blood vessels, such as Takayasu arteritis and giant cell arteritis, are associated with thoracic aortic aneurysms.
- Bicuspid aortic valve. Usually the valve between the lower left heart chamber and the aorta has three flaps. A bicuspid valve has only two. People who are born with a bicuspid aortic valve are more likely to get a thoracic aneurysm.
- Untreated infection. Though rare, it’s possible to get a thoracic aortic aneurysm if you’ve had an untreated infection such as syphilis or salmonella.
- Traumatic injury. Some people who are injured in falls or motor vehicle crashes get thoracic aortic aneurysms. But this is rare.
Anything that damages or weakens blood vessels may raise the risk of an aneurysm. Thoracic aortic aneurysm risk factors include:
- Age. Thoracic aortic aneurysms occur most often in people age 65 and older.
- Smoking and tobacco use. If you smoke or chew tobacco, it’s important that you quit. Using tobacco also can worsen an aneurysm and overall health.
- High blood pressure. Increased blood pressure damages the blood vessels in the body. This raises the risk of an aneurysm.
- Coronary artery disease. This type of heart disease causes reduced blood flow to the heart. It’s often caused by atherosclerosis. Atherosclerosis can damage the lining of a blood vessel, increasing the risk of an aneurysm. This is a more common risk in older people.
- Family history. You’re more likely to get an aortic aneurysm and rupture if you have a parent, brother, sister or child with one. You may develop aneurysms at a younger age.
If you’re at risk of an aortic aneurysm, you might get medicines to lower your blood pressure and relieve stress on weakened arteries.
Possible complications of a thoracic aortic aneurysm are:
- A tear in the wall of the aorta, also called an aortic dissection. This life-threatening condition causes bleeding into and along the aortic wall. Emergency surgery is needed to prevent death.
- Rupture of the body’s main artery, called an aortic rupture. If a tear in the aorta causes bleeding outside the aorta, it’s called an aortic rupture. This also is a life-threatening condition that needs treatment right away. In general, the larger the aneurysm, the greater the risk of rupture.
- Blood clots. Small blood clots can develop in the area of the aortic aneurysm. If a blood clot breaks loose from the inside wall of an aneurysm, it can block a blood vessel elsewhere in the body. This can possibly cause serious complications.
- Stroke. Signs and symptoms of stroke include weakness of or an inability to move one side of the body. It may be hard to speak.
To prevent an aneurysm, keep the blood vessels as healthy as possible. Try these healthy lifestyle tips.
- Don’t smoke or use tobacco.
- Control blood pressure and cholesterol levels.
- Keep a healthy weight and stay active.
- Eat nutritious foods.
Screening
Screening means that you have regular imaging tests, usually an echocardiogram, to look for an aneurysm.
Your healthcare professional may suggest screening for a thoracic aneurysm if:
- You have a parent, brother, sister, son or daughter with a genetic condition linked to thoracic aortic aneurysms. An example is Marfan syndrome.
- You have a family history of aortic aneurysms and wish to get pregnant.
If a screening test shows a larger than usual aorta or an aneurysm, the test is usually repeated within 6 to 12 months to look for changes.
Thoracic aortic aneurysms often don’t have symptoms. So they can be hard to diagnose. They are often found when an imaging test is done for a different reason.
If you have a thoracic aortic aneurysm, your healthcare professional may ask about your family’s medical history. Some aneurysms can run in families.
Tests
Tests are done to diagnose or screen for a thoracic aortic aneurysm. Tests may include:
- Echocardiogram. Sound waves show how blood moves through the heart and blood vessels, including the aorta. This test may be used to diagnose or screen for thoracic aortic aneurysms. A standard echocardiogram looks at the aorta from outside the body. If it doesn’t give enough details, a transesophageal echocardiogram may be done. This type looks at the aorta from inside the body.
- CT scan. X-rays make cross-sectional images of the body, including the aorta. This test can show the size and shape of an aneurysm.
- Heart MRI, also called a cardiac MRI. A magnetic field and radio waves create pictures of the heart and aorta. A heart MRI can diagnose an aneurysm and show its size and location. This test doesn’t use radiation. It may be an option to CT scans for people who need frequent imaging tests.
The goals of treatment for a thoracic aortic aneurysm are to:
- Stop the aneurysm from growing.
- Prevent aortic rupture.
Treatment depends on the aneurysm’s size and how fast it’s growing.
Treatment for thoracic aortic aneurysm may include:
- Regular health checkups, sometimes called watchful waiting.
- Medicines.
- Surgery.
Regular checkups
Small thoracic aneurysms may only need medicine and regular imaging tests to watch the aneurysm.
Usually you get an echocardiogram, CT or magnetic resonance angiography scan at least six months after your aneurysm is diagnosed. How often you need these tests depends on the cause and size of the aneurysm, and how fast it’s growing.
Medications
Medicines may be used to treat high blood pressure, high cholesterol and other conditions linked to aneurysms.
- Beta blockers. These medicines slow the heartbeat and lower blood pressure. They may reduce how fast the aorta is widening in people with Marfan syndrome.
- Angiotensin 2 receptor blockers (ARBs). These medicines may be used if beta blockers can’t be taken or if they don’t lower blood pressure enough. They are often recommended for people who have Loeys-Dietz syndrome even if they don’t have high blood pressure. Examples of ARBs include losartan (Cozaar), valsartan (Diovan) and olmesartan (Benicar).
- Statins. These medicines help lower cholesterol. They can help reduce the risk of blockages in the arteries and aneurysm complications. Examples of statins are atorvastatin (Lipitor), lovastatin (Altoprev), simvastatin (Zocor, FloLipid) and others.
Surgery or other procedures
Surgery is generally recommended for thoracic aortic aneurysms about 1.9 to 2.4 inches (about 5 to 6 centimeters) and larger. Surgery may be recommended for smaller aneurysms if you have a family history of aortic dissection or a condition linked to aortic aneurysm, such as Marfan syndrome.
The type of surgery done depends on:
- The cause of the aneurysm.
- Your overall health.
- The location of the aneurysm.
Types of surgeries and procedures for thoracic aortic aneurysms include:
- Open surgery. Most people with a thoracic aortic aneurysm have this major surgery. A surgeon removes part of the aorta damaged by the aneurysm. It’s replaced with a tube, called a graft, which is sewn into place.
- Aortic root surgery. This surgery is done to prevent an aortic aneurysm from rupturing. A surgeon takes out part of the aorta and sometimes the aortic valve. A graft replaces the removed part of the aorta. The aortic valve may be replaced with a mechanical or biological valve. If the valve is not removed, the surgery is called valve-sparing aortic root repair.
Endovascular aortic aneurysm repair (EVAR). This treatment is a less invasive option to open surgery. That means it uses small surgical cuts and may allow a faster recovery. The surgeon places a thin, flexible tube into a blood vessel, usually in the groin, and guides it to the aorta. A graft on the end of the catheter goes where the aneurysm is. Small hooks or pins hold the graft in place. The graft strengthens the weakened part of the aorta.
EVAR can’t be done on everyone. Ask your healthcare professional whether it’s right for you. After EVAR, you need regular imaging tests to make sure the graft is working correctly.
- Emergency surgery. A ruptured thoracic aortic aneurysm needs emergency surgery. This open-chest surgery is risky. There is a high chance of complications. That’s why it’s important to find and treat thoracic aortic aneurysms before they rupture.
References
- Aortic aneurysm. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health-topics/aneurysm. Accessed Nov. 11, 2024.
- Ostberg NP, et al. The genetics of thoracic aortic aneurysms and dissection: A clinical perspective. Biomolecules. 2020; doi:10.3390/biom10020182.
- Thoracic aortic aneurysms. Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/diseases-of-the-aorta-and-its-branches/thoracic-aortic-aneurysms. Accessed Nov. 11, 2024.
- Black JH, et al. Epidemiology, risk factors, pathogenesis, and natural history of thoracic aortic aneurysm. https://www.uptodate.com/contents/search. Accessed Nov. 11, 2024.
- Burke CR, et al. Clinical manifestations and diagnosis of thoracic aortic aneurysm. https://www.uptodate.com/contents/search. Accessed Nov. 11, 2024.
- Papadakis MA, et al., eds. Thoracic aortic aneurysms. In: Current Medical Diagnosis & Treatment 2025. McGraw Hill; 2025. https://accessmedicine.mhmedical.com. Accessed Nov. 11, 2024.
- Burke CR, et al. Management of thoracic aortic aneurysm in adults. https://www.uptodate.com/contents/search. Accessed Nov. 11, 2024.
- What is Marfan syndrome? National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/marfan-syndrome. Accessed Nov. 11, 2024.
- Rurali E, et al. Precise therapy for thoracic aortic aneurysm in Marfan syndrome: A puzzle nearing its solution. Progress in Cardiovascular Diseases. 2018; doi:10.1016/j.pcad.2018.07.020.
- Upchurch GR, et al. Society for Vascular Surgery clinical practice guidelines of thoracic endovascular aortic repair for descending thoracic aortic aneurysms. Journal of Vascular Surgery. 2021; doi:10.1016/j.jvs.2020.05.076.
- Nimmagadda R. Allscripts EPSi. Mayo Clinic. Nov. 5, 2024.
- AskMayoExpert. Thoracic aortic aneurysm (adult). Mayo Clinic; 2023.
- Medical review (expert opinion). Mayo Clinic. Jan. 17, 2020.
- Medical review (expert opinion). Mayo Clinic. Feb. 28, 2022.
- Libby P, et al., eds. Diseases of the aorta. In: Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed Nov. 11, 2024.
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