Uterine Polyps
Uterine polyps are growths attached to the inner wall of the uterus that expand into the uterus. Uterine polyps, also known as endometrial polyps, form as a result of cells in the lining of the uterus (endometrium) overgrowing. These polyps are usually noncancerous (benign), although some can be cancerous or can turn into cancer (precancerous polyps).
Uterine polyps range in size from a few millimeters — no larger than a sesame seed — to several centimeters — golf-ball-size or larger. They attach to the uterine wall by a large base or a thin stalk.
There can be one or many uterine polyps. They usually stay within the uterus, but they can slip through the opening of the uterus (cervix) into the vagina. Uterine polyps are most common in people who are going through or have completed menopause. But younger people can get them, too.
Signs and symptoms of uterine polyps include:
- Vaginal bleeding after menopause.
- Bleeding between periods.
- Frequent, unpredictable periods whose lengths and heaviness vary.
- Very heavy periods.
- Infertility.
Some people have only light bleeding or spotting; others are symptom-free.
When to see a doctor
Seek medical care if you have:
- Vaginal bleeding after menopause.
- Bleeding between periods.
- Irregular menstrual bleeding.
Hormonal factors appear to play a role. Uterine polyps are estrogen-sensitive, meaning they grow in response to estrogen in the body.
Risk factors for developing uterine polyps include:
- Being perimenopausal or postmenopausal.
- Being obese.
- Taking tamoxifen, a drug therapy for breast cancer.
- Taking hormone therapy for menopause symptoms.
Uterine polyps might be associated with infertility. If you have uterine polyps and you’re unable to have children, removal of the polyps might allow you to become pregnant, but the data are inconclusive.
The following tests might be used to diagnose uterine polyps:
Transvaginal ultrasound. A slender, wandlike device placed in the vagina emits sound waves and creates an image of the uterus, including its insides. A polyp might be clearly present or there might be an area of thickened endometrial tissue.
A related procedure, known as hysterosonography (his-tur-o-suh-NOG-ruh-fee) — also called sonohysterography (son-oh-his-tur-OG-ruh-fee) — involves having salt water (saline) injected into the uterus through a small tube placed through the vagina and cervix. The saline expands the uterus, which gives a clearer view of the inside of the uterus during the ultrasound.
- Hysteroscopy. This involves inserting a thin, flexible, lighted telescope (hysteroscope) through the vagina and cervix into the uterus. Hysteroscopy allows for viewing the inside of the uterus.
- Endometrial biopsy. A suction catheter inside the uterus collects a specimen for lab testing. Uterine polyps might be confirmed by an endometrial biopsy, but the biopsy could also miss the polyp.
Most uterine polyps are benign. This means that they’re not cancer. But, some precancerous changes of the uterus, called endometrial hyperplasia, or uterine cancers appear as uterine polyps. A tissue sample of the removed polyp is analyzed for signs of cancer.
Treatment for uterine polyps might involve:
- Watchful waiting. Small polyps without symptoms might resolve on their own. Treatment of small polyps is unnecessary for those who aren’t at risk of uterine cancer.
- Medication. Certain hormonal medications, including progestins and gonadotropin-releasing hormone agonists, may lessen symptoms of the polyp. But taking such medications is usually a short-term solution at best — symptoms typically recur once the medicine is stopped.
- Surgical removal. During hysteroscopy, instruments inserted through the device used to see inside the uterus (hysteroscope) make it possible to remove polyps. The removed polyp will likely be sent to a lab for examination.
If a uterine polyp contains cancer cells, your provider will talk with you about the next steps in evaluation and treatment.
Rarely, uterine polyps can recur. If they do, they need more treatment.
References
- Stewart EA. Endometrial polyps. https://www.uptodate.com/contents/search. Accessed July 18, 2022.
- Nijkang NP, et al. Endometrial polyps: Pathogenesis, sequelae and treatment. Sage Open Medicine. 2019; doi:10.1177/2050312119848247.
- Committee opinion: The use of hysteroscopy for the diagnosis and treatment of intrauterine pathology. The American College of Obstetricians and Gynecologists. 2020. https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2020/03/the-use-of-hysteroscopy-for-the-diagnosis-and-treatment-of-intrauterine-pathology. Accessed July 18, 2022.
- DeCherney AH, et al., eds. Benign disorders of the uterine corpus. In: Current Diagnosis & Treatment: Obstetrics & Gynecology. 12th ed. McGraw Hill; 2019. https://accessmedicine.mhmedical.com. Accessed July 18, 2022.
- Heavy menstrual bleeding. Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/blooddisorders/women/menorrhagia.html. Accessed July 18, 2022.
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