Cleft lip and palate are birth defects that affect the upper lip and the roof of the mouth.

There are many causes of cleft lip and palate. Problems with genes passed down from 1 or both parents, drugs, viruses, or other toxins can all cause these birth defects. Cleft lip and palate may occur along with other syndromes or birth defects.

A cleft lip and palate can:

  • Affect the appearance of the face
  • Lead to problems with feeding and speech
  • Lead to ear infections

Babies are more likely to be born with a cleft lip and palate if they have a family history of these conditions or other birth defects.

A child may have one or more birth defects and the severity can vary significantly.

A cleft lip may be just a small notch in the lip. It may also be a complete split in the lip that goes all the way to the base of the nose.

A cleft palate can be on one or both sides of the roof of the mouth. It may go the full length of the palate.

Other symptoms include:

  • Change in nose shape (how much the shape changes varies)
  • Poorly aligned teeth

Problems that may be present because of a cleft lip or palate are:

  • Failure to gain weight
  • Feeding problems
  • Flow of milk through nasal passages during feeding
  • Poor growth
  • Repeated ear infections
  • Speech difficulties

A physical exam of the mouth, nose, and palate confirms a cleft lip or cleft palate. Medical tests may be done to rule out other possible health conditions.

Surgery to close the cleft lip is often done when the child is between 2 to 9 months old. Surgery may be needed later in life if the problem has a major effect on the nose area. Some patients may receive tympanostomy tubes during the surgery also.

A cleft palate is most often closed within the first year of life so that the child’s speech develops normally. Sometimes, a prosthetic device is temporarily used to close the palate so the baby can feed and grow until surgery can be done.

Continued follow-up may be needed with speech therapists and orthodontists.

Cleft palate; Craniofacial defect

Dhar V. Cleft lip and palate. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 336.

Felton M, Lee JW, Balumuka DD, Arneja JS, Chadha NK. Early placement of ventilation tubes in infants with cleft lip and palate: a systematic review. Otolaryngol Head Neck Surg. 2018;158(3):459-464. PMID: 29161200 pubmed.ncbi.nlm.nih.gov/29161200/.

Wang TD, Milczuk HA. Cleft lip and palate. In: Flint PW, Francis HW, Haughey BH, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 188.

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